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Advanced Hypothesis, Theory & Discussion
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Topic starter
14/07/2026 8:23 am
Just wondering if any of yall have been on HRT for over 20 years? If so do you notice any negative long term side effects?
14/07/2026 8:54 am
Dont think TRT for men has been actively used for 20 years already.. correct me if I'm wrong tho.
14/07/2026 9:16 am
No I believe you are right nby. TRT is fairly new and most Dr. still dont understand the concept fully. You may find some that have been on for maybe 5-8 years, maybe.
Topic starter
14/07/2026 9:45 am
No I believe you are right nby. TRT is fairly new and most Dr. still dont understand the concept fully. You may find some that have been on for maybe 5-8 years, maybe.
Well have any of yall been on for 5+ years that have noticed long term side effects?
This post was modified 3 weeks ago by admin
14/07/2026 10:08 am
Well have any of yall been on for 5+ years that have noticed long term side effects?
I'm sure you're smart enough to find the possible side effects, especially on prolonged use;
- Higher BP
- Bad cholesterol
- Prostate
- Acne
- Testicular atrophy
However all of this is different per user. TRT is an all-in package which should also monitor your health periodically, like via a blood panel.
I think a few have been on TRT for a few years, wait for them to chime in.
14/07/2026 10:35 am
3 + years... regular CBC, Chem,, LFT's, TFT's all spot on. HDL/LDL,chol, triglyceride levels are very good...my only issue is with fatigue, daytime sleepiness, "brain fog," anhedonia, that hasn't changed with TRT to the extent that I was hoping for and has actually worsened over the months.. Most likely due to mild sleep apnea(may be a side affect of TRT/AAS use) which I am currently being treated for and definitely from prior substance use > misuse > abuse history(opiates)....
Other than that I am very happy with the results...
Topic starter
14/07/2026 11:00 am
3 + years... regular CBC, Chem,, LFT's, TFT's all spot on. HDL/LDL,chol, triglyceride levels are very good...my only issue is with fatigue, daytime sleepiness, "brain fog," anhedonia, that hasn't changed with TRT to the extent that I was hoping for and has actually worsened over the months.. Most likely due to mild sleep apnea(may be a side affect of TRT/AAS use) which I am currently being treated for and definitely from prior substance use > misuse > abuse history(opiates)....
Other than that I am very happy with the results...
I seen you write in another post you were on androgel what do your levels test at on that? Possibly you have fatigue and brain fog b/c ur test levels still arent high enough?
This post was modified 3 weeks ago by admin
14/07/2026 11:21 am
700 last month.. 4 pumps day, 1.62%
