Glutamine, ALA- Bio...
 
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Glutamine, ALA- Bioting


Andrea
(@andrea)
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Hey!! I'm currently cutting and I was told that Glutamine and ALA were good supplements to take. I was also told that if I take ALA I need to supplement it with Biotin. Is it okay to put Glutamine in my protein shake? Do I need to do it in the morning or before bed? What about ALA? Should I just take this on high/cheat days? What about Biotin? And how much of each? Thanks!!!

Stats:
Female
5'8
140-145 lbs.


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str8flexed
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almost all of glutamine is converted to alanine in the intestinal wall (glutamine alanine cycle), and the alanine is then sent to the liver via the portal vein where it is utilized for gluconeogenesis. "Under NO CIRCUMSTANCES, does glutamine make it past the intestinal wall in appreciable amounts." - Dr. Donald Layman, Professor of Nutritional Science at university of Illinois who's specialty is in amino acids... I just discussed this topic with him yesterday

very expensive glucose if you ask me.

Limitations are for people that have them and excuses are for people that need them.

"Per Ferrum, ad astra"... Through iron, the stars
- Mel Siff

Bitch smacking pseudo-scientists since 2010.


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Andrea
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Should I take them or not then?


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Gazza
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Posted by: @Andrea
Should I take them or not then?

hahaha


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str8flexed
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Posted by: @Andrea
Should I take them or not then?

Limitations are for people that have them and excuses are for people that need them.

"Per Ferrum, ad astra"... Through iron, the stars
- Mel Siff

Bitch smacking pseudo-scientists since 2010.


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Andrea
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Posted by: @str8flexed
Should I take them or not then?

I'm talking about the ALA. What about CLA?


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str8flexed
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well when you say "them" i can only assume you are referring to both of THEM. In any case ala is a very worthwhile supp, the jury is still out on CLA

Limitations are for people that have them and excuses are for people that need them.

"Per Ferrum, ad astra"... Through iron, the stars
- Mel Siff

Bitch smacking pseudo-scientists since 2010.


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Ras
 Ras
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Why is this post in this section?


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omnibus
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Posted by: @str8flexed
almost all of glutamine is converted to alanine in the intestinal wall (glutamine alanine cycle), and the alanine is then sent to the liver via the portal vein where it is utilized for gluconeogenesis.  "Under NO CIRCUMSTANCES, does glutamine make it past the intestinal wall in appreciable amounts." - Dr. Donald Layman, Professor of Nutritional Science at university of Illinois who's specialty is in amino acids... I just discussed this topic with him yesterday

very expensive glucose if you ask me.

str8,

Why does l-glutamine interfere with my sleep?I thought it was the glutamine acting as an exitatory amino but if it doesn't get into the bloodstream...what about alanine,is it exitatory?


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str8flexed
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i'm not sure... possibly could be because it requires so much action from the gut and sphlanic bed in the small intestine during digestion... causing more nervous activity... possibly interfering with sleep? that would be my guess... I'll as Dr. Layman when he gets back from vacation... a good question b/c I have heard of that side effect before

Limitations are for people that have them and excuses are for people that need them.

"Per Ferrum, ad astra"... Through iron, the stars
- Mel Siff

Bitch smacking pseudo-scientists since 2010.


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Ras
 Ras
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Glutamine is a precursor to both glutamate (excitatory) and GABA (inhibitory), but if Layne's research holds true (I believe it does and has been amply demonstrated), I would suggest that the hepatic gluconeogenesis could be responsible in some manner for a disruption in the sleep-wakefulness cycle. Circadian rhythmicity has a fairly significant effect on glucose regulation.


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str8flexed
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a very good point ras!

Limitations are for people that have them and excuses are for people that need them.

"Per Ferrum, ad astra"... Through iron, the stars
- Mel Siff

Bitch smacking pseudo-scientists since 2010.


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roadrunner
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his name is Dr. Layman?

did you make that up?


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str8flexed
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um... that's a pretty common last name

-Layne "can you hear me all the way back there in the 2nd grade?"

Limitations are for people that have them and excuses are for people that need them.

"Per Ferrum, ad astra"... Through iron, the stars
- Mel Siff

Bitch smacking pseudo-scientists since 2010.


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roadrunner
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speaking in layman's terms is a common saying. I just thought it was ironic for a professor to have that as his last name, as that is what his profession entails. chalk it up to a somewhat nerdish sense of humor

the juvenile interpretation hadn't crossed my mind


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