Toremifene PCT

Then switch to Nolvadex. First week 40, 20 the weeks after, depending on how long your cycle was.

x2 >>>>>>>>nolva works just as good brother

Nolva reduces IGF and GH

Neuroendocrine Regulation of Growth Hormone and Androgen Axes by Selective Estrogen Receptor Modulators in Healthy Men

Birzniece V, Sata A, Sutanto S, Ho KKY. Neuroendocrine Regulation of Growth Hormone and Androgen Axes by Selective Estrogen Receptor Modulators in Healthy Men. J Clin Endocrinol Metab:jc.2010-1477. Neuroendocrine Regulation of Growth Hormone and Androgen Axes by Selective Estrogen Receptor Modulators in Healthy Men

Context: In men, the stimulation of GH and inhibition of LH secretion by Testosterone requires aromatization to estradiol. Tamoxifen, a selective estrogen receptor modulator (SERM ), possesses central estrogen antagonistic effect but peripheral hepatic agonist effect, lowering IGF-1. Thus, tamoxifen is likely to perturb the neuroendocrine regulation of GH and gonadal axes. Raloxifene, a SERM, is used for therapy of osteoporosis in both sexes. Its neuroendocrine effects in men are poorly understood.

Objective: The aim was to compare the impact of raloxifene and tamoxifen on GH-IGF-I and gonadal axes in healthy men.

Design: We conducted a randomized, open-label crossover study.

Patients and Intervention: Ten healthy men were randomized to 2-wk sequential treatment with tamoxifen(10 and 20 mg/d) and raloxifene (60 and 120 mg/d), with a 2-wk intervening washout period.

Main Outcome Measures: We measured the GH response to arginine and circulating levels of IGF-I, LH, FSH, testosterone, and SHBG.

Results: Tamoxifen, but not raloxifene, significantly reduced IGF-I levels by 25 {+/-} 6% (P < 0.01) and increased SHBG levels by 20 {+/-} 7% (P < 0.05) at the higher therapeutic dose. There was a nonstatistically significant trend toward a reduction in the GH response to arginine with both SERMs . Both drugs significantly increased LH, FSH, and testosterone concentrations. The mean increase in testosterone (40 vs. 25%; P < 0.05) and LH (70 vs. 30%; P < 0.01) was significantly greater with tamoxifen than with raloxifene treatment.

Conclusions: Tamoxifen, but not raloxifene, reduces IGF-I levels. Both SERMs stimulate the gonadal axis, with tamoxifen imparting a greater effect. We conclude that in therapeutic doses, raloxifene perturbs theGH and gonadal axes to a lesser degree than tamoxifen.

I've only had vision problems during my 1st PCT years ago, was using it at 50mg day. These days I use 100/100/100/50/50/50... without any problems.
Avoid nolva, try clomid at 25mg twice a day.

I used nolvadex my last pct I did 60, 40, 40, 20 weeks 1-4. This was years ago.

nolva

age old debate clomid v.s nolva= priceless

Whatever you choose, make sure you use aromasin. Aromasin + nolva is a golden PCT.

Posted by: @rainier

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Whatever you choose, make sure you use aromasin. Aromasin + nolva is a golden PCT.

12.5 eod?